Treatment of knee pain should be based on the cause accordingly. Common causes of knee pain include knee arthritis, knee synovitis, chondromalacia patella, etc. The cause should be clarified in time and then treated. 1. Knee osteoarthritis: You can take pain-control medications, such as acetaminophen, etc. You can also take non-steroidal anti-inflammatory drugs, such as celecoxib. In addition, taking Doxycycline, Glucosamine, Avocado Soybean Unsaponifiables, etc. can also improve the symptoms. 2. Knee synovitis: glucocorticoids, celecoxib and other drugs can be applied. 3. Chondromalacia patella: commonly used drugs are ibuprofen extended-release capsules, celecoxib, aspirin, etc., which can play an anti-inflammatory and pain-relieving role. Serious knee pain should go to the hospital in a timely manner, after the cause is clear, under the guidance of the doctor to take the above drugs, do not take medication.