The first question that many patients and their families ask is whether epilepsy surgery is minimally invasive, because they want to make a small cut on their scalp or drill a small hole to completely cure their epilepsy. The first question is whether the epilepsy surgery is minimally invasive. This is not very traumatic and does not even require hospitalization, but there is no certainty of efficacy and the patient spends money for nothing. This situation is found in Fujian, Beijing, and many other places in China, and it makes us very sad every time we meet a patient who has been treated in this way. We cannot blame the patients who are desperate for treatment, and we cannot comfort the patients who need surgical treatment without principle, because no matter how high the professional team is and how experienced they are, epilepsy surgery is a traumatic craniotomy, and there are risks. All we have to do is to use skilled techniques to minimize the trauma of the surgery. When localizing the epileptogenic focus for diagnosis, we patiently study the patient’s seizure manifestations and locate the epileptogenic focus by non-invasive means such as skilful computerized localization analysis of scalp EEG and advanced imaging examination as much as possible. However, in cases where the above methods are difficult to locate accurately, especially in cases where it is estimated that the epileptogenic focus is closely related to important functional areas, intracranial electrodes must be buried to precisely locate the epileptogenic focus and functional areas to improve the effectiveness and safety of surgery as much as possible. In terms of research on minimally invasive epilepsy surgery, our epilepsy center has made outstanding contributions to the epilepsy surgery community. 80 and 1500 cases of selective hippocampal amygdala resection through the inferior temporal gyrus and anterior temporal lobe hippocampal amygdala resection through the temporal foramen ovale have been successfully performed respectively. The patients can get out of bed and walk on the same day. The outstanding academic achievements have been recognized by many domestic and foreign colleagues, including Prof. Tomokatsu Hori.