Cholesterol is the main component of atherosclerotic plaque in blood vessels. As long as cholesterol can be controlled to meet the standard range, such as controlling diet, proper exercise, and taking statin lipid-lowering drugs, we can prevent the occurrence of atherosclerotic cardiovascular disease events. That is, lowering cholesterol can reduce the occurrence of cardiovascular events. So statins are very important and should not be ignored. Some people are afraid to take statins when they see that there are many side effects written on the instructions, and they hear about various side effects of statins and exaggerate them, so they give up taking statins and take Chinese herbal medicine Panax ginseng powder or a certain country’s health product deep-sea fish oil instead, causing cardiovascular disease to worsen and even thrombosis, leading to serious consequences such as myocardial infarction, pulmonary infarction and cerebral infarction. In fact, the safety of statin drugs is very good, as long as the correct use of drugs under the guidance of doctors, do not drink alcohol, regular review of biochemical blood indicators, rarely occur adverse reactions. If, after the doctor’s assessment, the patient has more side effects after applying statins, and the patient really cannot tolerate statins, in this case, we can consider other cholesterol-lowering drugs. For patients with adverse reactions to higher doses of statins, a combination of low-dose statins and ezetimibe is the preferred treatment option. Depending on the patient, we can use different doses and combinations of medications. Many people are treated with statins because of high blood lipids or because of cardiovascular disease. As required, regular biochemical examinations are required after medication, but many people take the medication and never have blood tests. This is absolutely wrong. We must avoid this kind of fluke and do not avoid treatment, so how often do we need to review biochemical indicators after taking a statin? People who have just started taking statins should have their blood lipids, liver function, heart function and kidney function checked within 6 weeks of taking the medication. The purpose of reviewing the lipid index is to understand the effect of treatment and the need to adjust the drug dose; the purpose of reviewing the transaminase and creatine kinase is to understand whether there are any adverse reactions in the liver and muscles after taking statin. Statins can be divided into water-soluble statins (such as pravastatin and resevastatin) and fat-soluble statins (such as simvastatin and lovastatin). Some scholars believe that water-soluble statins have little effect on the liver and that taking these statins after drinking alcohol has little effect on the liver, but this is only relative. All kinds of statins have potential adverse effects on the liver, so it is better not to take statins after drinking. And we should choose the type of statin reasonably and appropriately according to our own economic conditions. Some people say that statins do not prevent heart disease, but after the 4S study in 1994, there have been dozens of rigorously designed large clinical trials that have fully and repeatedly demonstrated the superior efficacy of statins in preventing cardiovascular disease. The renal safety of statins has also been demonstrated in numerous clinical studies. Some people say that statins can cause rhabdomyolysis, but the incidence is only 1 in 10 million, a small probability event. In conclusion, statins have an irreplaceable role in the prevention of cardiovascular events, and there are many academic studies that confirm this view. We will not list them all here. Statins are inexpensive and cost-effective. We need to take them properly, take them appropriately, and monitor our liver and kidney function. Let the statins protect us.