The clinical manifestations of neuroblastoma are different in different parts of the body, which are mainly manifested as abdominal distension, dyspnea, mass and so on. 1. Neuroblastoma appears in the abdominal cavity, mostly in the retroperitoneal position, and the patients may have the symptoms of abdominal distension, abdominal bulge and abdominal hard lumps and so on. 2. Thoracic neuroblastoma, with the continuous growth of the tumor, affects the lung tissues and functions, and the patient may have chest tightness, dyspnea and so on. 3. Paraspinal neuroblastoma can press the spine or press the nerve root, which will cause invasion to the nervous system, and then the patient will have abnormal activities, such as unstable walking, difficulty in standing, and in severe cases, paraplegia will occur. 4. Neuroblastoma or metastatic foci of neuroblastoma occurring in legs, hips and other bone joints will affect the hematopoietic function of the patients, and the patients may suffer from anemia, platelet reduction and so on. If the patients have the above symptoms, they should go to regular hospitals for consultation in time, follow the diagnosis and treatment opinions of specialists, actively cooperate with treatment, and follow up regularly.