Currently, the treatment of choice for chronic granulocytic leukemia is targeted therapy, usually using tyrosine kinase inhibitors such as imatinib, dasatinib, nilotinib, etc., which may be combined with chemotherapy and bone marrow transplantation if the disease is in advanced stages. With standardized treatment, the progression of chronic granulocytic leukemia can usually be effectively controlled. In a few cases, complete cure is possible. 1. Targeted drugs are the first choice and the best treatment for patients with chronic granulocytic leukemia, such as imatinib. These targeted drugs work by reducing the production of abnormal white blood cells, usually causing less damage to normal cells and mild side effects. 2. If the disease has progressed to an advanced stage, it is recommended to combine chemotherapy with targeted therapies, such as marfan and cytarabine. 3. Bone marrow transplantation, also known as stem cell transplantation, is the only chance for a complete cure for chronic granulocytic leukemia. However, bone marrow transplantation is risky and has a high incidence of serious complications, and should be done carefully under the supervision of a physician. It is advisable to consult a medical professional for the specific treatment of chronic granulocytic leukemia and to follow the doctor’s instructions, rather than making unauthorized decisions.