The humoral factors involved in the regulation of cardiovascular activity are renin, angiotensin, epinephrine, norepinephrine, vasopressin, vascular endothelial vasodilator substances, etc.
1. Renin-angiotensin system RAS factors: they play an important role in the stabilization of cardiovascular function and the regulation of myocardial vascular smooth muscle function, including renin, angiotensin, aldosterone and other substances.
2. Catecholamines: including epinephrine, norepinephrine and so on. They have the function of regulating peripheral vascular contraction or diastole, increasing cardiac output and elevating blood pressure.
3. Vasopressin: It has the effect of antidiuretic and elevating blood pressure.
4. Endothelial vasodilator substances: including nitric oxide, prostaglandins, endothelin and so on. It has the function of regulating local vasodilation and contraction.