High blood pressure after taking antihypertensive drugs may be caused by irrational antihypertensive treatment program, failure to improve lifestyle, secondary hypertension, etc. It can be treated by adjusting antihypertensive treatment program, improving lifestyle and treating secondary hypertension. 1. Unreasonable antihypertensive treatment program: If the dosage of antihypertensive drugs is too small or the use of inappropriate antihypertensive drugs causes blood pressure not to be controlled after taking antihypertensive drugs, the doctor should be consulted to adjust the dosage of the drugs in a timely manner or to replace with other antihypertensive drugs, such as hydrochlorothiazide, furosemide and so on. 2. Lifestyle is not improved: not paying attention to improve the lifestyle while taking medication can also lead to the situation that the blood pressure still does not fall after taking medication. You should pay attention to lifestyle adjustments, such as quitting smoking, reducing salt intake, losing weight, regular work and rest, and so on. 3. Secondary hypertension: secondary hypertension is difficult to control blood pressure through antihypertensive medication, and different treatments need to be taken according to the specific disease. For example, renal vascular hypertension requires percutaneous renal arterioplasty, primary aldosteronism requires spironolactone treatment and surgical removal of adrenocortical adenoma. Therefore, after taking antihypertensive drugs, the blood pressure is still very high, should go to the hospital in time to improve the examination, to clarify the cause of the disease and then give targeted treatment.