Children’s constipation can be regulated by oral lactulose or probiotics, and with dietary structure and physical exercise for treatment. And according to the triggering factors of constipation to give targeted treatment. The most commonly used drugs for constipation, such as lactulose, lactulose is a laxative, can maintain regular bowel movement with probiotics (such as Lactobacillus acidophilus tablets) to regulate the intestinal flora imbalance, thereby relieving constipation. At the same time, you should exercise more and drink more water, which can promote defecation. If persistent constipation can not be relieved, we need to do intestinal ultrasound to exclude congenital megacolon, if it is megacolon can still take conservative treatment. However, if the conservative treatment fails or the child’s condition is serious or does not have the conditions for radical surgery, a colostomy can be performed. It is best to have radical surgery for congenital megacolon. All of the above medications should be taken under medical supervision.