A biopsy report confirms the diagnosis of Barrett’s esophagus, and the tissue as well as the cytological pattern is observed through pathological examination to clarify whether it is Barrett’s esophagus or not. Barrett’s esophagus, or Barrett’s esophagus, is a pathological change in the inner surface of the esophagus. For patients suspected of having Barrett’s esophagus, a small amount of tissue sample of the suspected lesion is collected for staining while observing the condition in the esophagus, and the cellular morphology is observed to determine whether there is heterogeneous hyperplasia or not to clarify whether it is Barrett’s esophagus. Patients suspected of having Barrett’s esophagus are advised to go to a regular hospital in time, cooperate with the doctor for examination, make a clear diagnosis, and take active treatment to avoid delay in diagnosis and treatment.