For advanced kidney cancer, it is mainly that the kidney tumor breaks through the renal fat capsule and invades the neighboring organs, such as adrenal glands or distant metastasis of the tumor has occurred. Therefore the survival cycle of patients will not be more than 2 years if they do not have any treatment. However, patients with advanced kidney cancer can also undergo palliative treatments, such as cytokine therapy and immunotherapy, in which some patients can benefit from these treatments to slow down the progression of advanced kidney cancer. If the comprehensive treatment is effective, it can improve the survival rate of patients, and the survival rate can be maintained for 3-5 years in the course of drug treatment. However, it is also necessary to make a comprehensive evaluation according to the effectiveness of the medication used by the patients. Therefore, for patients with advanced kidney cancer who have already developed distant metastasis or organ invasion and have lost the best time for surgical treatment, the quality of survival can only be improved through comprehensive treatment.