Most postherpetic neuralgia can be fully recovered from shingles. Herpes zoster is a skin damage caused by varicella zoster virus infection, the viral infection will damage the local nerves, resulting in neuralgia and other sequelae. Postherpetic neuralgia can be treated with nutritive nerve and anti-inflammatory analgesic drugs, commonly used analgesic drugs can choose ibuprofen, diclofenac sodium and so on; nutritive nerve drugs can choose methylcobalamin and so on. At present, calcium channel modulators such as pregabalin and gabapentin also have good efficacy in improving post-pain neuralgia. Through active treatment, most of the neuralgia symptoms will gradually recover. Postherpetic neuralgia requires prompt medical attention, and all medications should be used under the guidance of a medical professional.