When patients wear new myopia glasses and feel their eyes are tired, it may be caused by not adapting to wearing glasses, discomfort of glasses prescription, discomfort of glasses frames and so on. 1. Not adapting to wearing glasses: patients temporarily do not adapt to the feeling of wearing new glasses, especially if they have never worn glasses before, because they have never worn glasses before, so they need an adaptation process for new glasses. Therefore, at the beginning of wearing glasses, patients may have tired eyes. 2. Discomfort of eyeglasses prescription: If the prescription of the new eyeglasses is not suitable for the patient, especially if the prescription of the eyeglasses is high, the patient may have nausea, vomiting and other discomforts in addition to the tiredness of the eyes. 3. Eyeglasses frame discomfort: As the new eyeglasses frame is too big or not suitable for the patient, it leads to great working pressure on the eye muscles, so the patient may wear new myopia glasses and his eyes are very tired. It is recommended that patients who experience discomfort from wearing eyeglasses should consult a doctor in a timely manner to assess their condition and follow the doctor’s instructions for treatment and appropriate eyeglasses.