After staying up all night causing patients to have numbness in the hands and feet, it does not necessarily lead to sudden death completely, but this situation also rings alarm bells for patients. If one side of the hand and foot numbness, this situation should be considered as acute cerebrovascular disease, because staying up late is not good for the body, so one side of the hand and foot numbness may be transient cerebral ischemic attack, possibly due to cerebral infarction or cerebral hemorrhage and other diseases. In this case, the patient must immediately consult the emergency department or neurology department of the hospital to clarify through the doctor’s examination and improve the head CT or even magnetic resonance brain function imaging, and then actively carry out treatment. Patients should not often stay up late, after often staying up late will lead to endocrine disruption, sudden rise in blood pressure, as well as the incidence of cardiovascular and cerebrovascular diseases are significantly increased, so staying up late and sudden death also have a certain relationship.