Black spot polyposis, or black spot polyp syndrome, does not usually affect life expectancy if the condition is stable and not cancerous. If the polyp becomes cancerous, it can affect life expectancy. As a dominant autosomal disorder, the determination of whether life expectancy will be affected by the syndrome depends on the circumstances of each case and cannot be generalized. Patients with macular polyp syndrome can often suffer from complications such as intestinal obstruction, intestinal bleeding, anemia, and polyp cancer. Treatment is aimed at relieving symptoms, improving quality of life, and avoiding serious complications. Currently, endoscopic treatment (regular follow-up for polyps less than 0.5cm, endoscopic resection for polyps ≥0.5cm) and surgery are available. Therefore, patients with macular polyp syndrome need to strengthen their daily life management, cooperate with doctors for active treatment, and go to the hospital for review on time, so that doctors can understand the effect of treatment to avoid delaying the condition.