Holmium laser lithotripsy includes anesthesia and preoperative preparation, placement of ureteroscope, laser lithotripsy and stone extraction, and postoperative management. 1. For anesthesia and preoperative preparation, the patient was placed in the lying position and anesthesia was administered by the anesthesiologist. After anesthesia, the legs were spread apart to keep the lithotomy position and expose the patient’s urethral orifice, and then disinfect and spread the towel. 2. The ureteroscope is inserted through the urethral orifice, and the ureteroscope is inserted through the urethral orifice to find the location of the patient’s stone with the help of a mirror. 3. Laser lithotripsy, after locating the stone through the ureteroscope, a laser guide wire is inserted, the holmium laser is used to break up the stone, and the stone is removed with a mesh basket, and a D-J tube is left in place. 4. Postoperative treatment, generally, the patient is left with a catheter, which is removed on the next day. It is recommended to actively seek medical advice and follow the doctor’s instructions.