If the pain is relieved and there are no other symptoms after opening and draining the pulp of apical abscess, anti-inflammatory drugs are not needed. If the pain is still not relieved or accompanied by systemic symptoms, anti-inflammatory drugs can be taken to assist in the treatment, as follows. 1. No need to take anti-inflammatory drugs: Usually, after opening the pulp, the exudate and pus from the root tip will be drained through the root canal, and the pressure in the root tip will be relieved, and the pain will be relieved. There is no need to take anti-inflammatory drugs in this case. 2. Anti-inflammatory drugs can be taken: If the affected tooth still feels pain, the pus in the root canal continues to overflow, or accompanied by symptoms of elevated temperature and generalized weakness, anti-inflammatory drugs can be taken, such as metronidazole, tinidazole and so on. All of the above drugs should be used under the guidance of a doctor. It is recommended to go to the hospital to receive regular treatment.