Apical hypertrophic cardiomyopathy requires medication. Apical hypertrophic cardiomyopathy can be improved by taking oral medications such as beta-blockers, calcium channel blockers, and antiarrhythmics. 1. β-blockers: they can slow down the heart rate, reduce myocardial contractility and myocardial oxygen consumption, and improve myocardial compliance, thus relieving symptoms such as chest pain, dyspnea and syncope, such as metoprolol and bisoprolol. 2. Calcium channel blocker: Verapamil has good effect in the treatment of apical hypertrophic cardiomyopathy, and its mechanism is to weaken myocardial contractility, improve myocardial compliance and filling degree, improve exercise tolerance, improve symptoms, and most of the people who are ineffective in β-blocker switch to isobaric pacing are effective. 3.Class I antiarrhythmic drugs: bis-isoproterenol is a class I antiarrhythmic agent, and has strong negative inotropic effect, which can slow down the left ventricular systolic blood ejection rate, reduce the subaortic pressure step difference, and improve the symptoms. 4. Class III antiarrhythmic drugs: small dose amiodarone is more effective in treating and preventing supraventricular and ventricular arrhythmias in apical hypertrophic cardiomyopathy, and can slow down the heart rate, improve the diastolic function of the heart, alleviate the symptoms, and improve the exercise tolerance, which can significantly reduce the incidence of sudden death, and improve the prognosis, and it is the most effective drug at present. Patients with apical hypertrophic cardiomyopathy should seek medical attention in a timely manner, according to the condition, under the guidance of the doctor to take medication.