The dipyridamole antihypertensive drugs are normally not damaging to the kidneys. Dipyridamole antihypertensive drugs refer to a class of dihydropyridine calcium antagonists, including nifedipine, amlodipine, lacidipine, etc. They can inhibit the transmembrane transport of calcium ions into cardiac muscle and smooth muscle cells, inhibit the release of calcium ions, reduce vasoconstriction, and lower blood pressure. Diphenhydramine antihypertensive drugs are mainly metabolized into pharmacologically inactive substances by the liver, and most of the water-soluble metabolites are excreted in the urine, with no accumulation in the body and no effect on the kidneys. When taken normally, the drugs do not damage the kidneys. Diphenhydramine antihypertensive drugs may appear liver function abnormalities, dizziness, flushing, blood pressure drop, swelling of the lower limbs, allergic reactions, gastrointestinal reactions and other adverse reactions, the use of drugs need to be under the guidance of a professional doctor, it is recommended to consult a doctor, standardized treatment.