Purpura patients with subcutaneous bleeding may be caused by various reasons such as reduced platelet count or abnormal function, abnormal blood vessel wall, reduced or dysfunctional coagulation factors, etc. Specific treatments are as follows: 1. General therapy: 1. At the early stage of the disease, activities should be reduced, trauma should be avoided, and bed rest should be given when platelets are low; 2. Active prevention and control of infection, aspirin can cause bleeding and should be avoided. To reduce bleeding tendency, vitamin C can be used routinely; 3. Give adequate amount of liquid and easy to digest diet to avoid oral mucosa damage. Second, drug treatment: 1, glucocorticoids: the drug of choice for treatment, can inhibit the destruction of platelets by the mononuclear macrophage system, and stimulate bone marrow hematopoiesis and the release of platelets to peripheral blood. Commonly used drugs include prednisone acetate, dexamethasone, methylprednisolone, etc.; 2. Immunosuppressants: Applicable to those who have poor effect of glucocorticoid treatment, and can also be used in combination with glucocorticoids to improve the efficacy. Commonly used drugs include vincristine, cyclophosphamide, azathioprine, etc.; 3. Anti-estrogens: Estrogens inhibit platelet production and enhance the ability of mononuclear macrophages to destroy platelets. Commonly used drugs include Danazol, Tamoxifen, etc. Third, emergency treatment: Applicable to those with severe and extensive subcutaneous bleeding. The first treatment is blood transfusion, the purpose of which is to rapidly replenish blood components in the body to help stop bleeding and maintain life, commonly used methods are fresh frozen plasma or platelets and other blood products intravenous infusion. Next is rehydration therapy, the purpose is to urgently replenish blood volume, can use a large amount of saline rapid intravenous drip. Lastly, hemostatic treatment is performed to avoid further blood loss, and commonly used drugs are tranexamic acid and posterior pituitary hormone.