Hypertrophy of the limbs is usually caused by excessive secretion of growth hormone (GH) by the pituitary gland. In adolescents, gigantism is formed when the epiphysis is not closed; after puberty, the epiphysis has fused, and then acromegaly is formed; in a few cases, the disease starts in adolescence and continues to develop in adulthood, forming acromegaly gigantism. So, what are the methods to prevent hypertrophy of the limbs? The following is a brief introduction: 1. Prevention of gigantism and acromegaly is still one of the more common pituitary tumors, which not only affects the skeleton, but also affects a variety of organs in the body, and has many late complications and is very serious. The focus of prevention of this disease is on early detection, so for suspected patients with rapid growth and significant increase in height, the blood GH concentration should be tested regularly and early. Head butterfly saddle X-ray or pituitary CT examination should be performed for early diagnosis. 2.When patients have early surgery or radiotherapy, GH secretion often returns to normal without sequelae, but there are still many patients who have recurrence after treatment and often have multiple organ lesions or even failure, and most of them have hypopituitarism, therefore, no matter after surgery or radiotherapy, regular observation is still needed, and GH, plasma phosphorus, blood sugar and pituitary hormone testing should be done regularly. If hypopituitarism is detected, in addition to hormone replacement, increased nutrition, increased protein and multivitamin intake, the occurrence of crisis should be guarded.