A red pimple on the face that hurts a little when touched may be acne, and it may also be acne with an inflammatory reaction. Inflammatory reactions sometimes appear as redness and swelling, or even pustules. If you have red pimples on your face and they are painful, you need to use anti-inflammatory medication. Anti-inflammatory medication can be chosen from roxithromycin or doxycycline, and also from memantine. If the inflammation is more obvious purulent, you also need to use amoxicillin. Generally, topical medications can use clindamycin gel, mupirocin cream or mucopolysaccharide polysulfate cream, which are good choices.