The possible clinical causes for that recess in the middle of the two ribs are thoracic costochondritis, intercostal neuritis, and some gastrointestinal disorders. Costal cartilage is characterized by swelling, pain, and discomfort in movement of the thoracic cartilage. Intercostal neuritis is characterized by pins and needles and burning pain in the innervated area of the intercostal nerves, which can be exacerbated by coughing, deep breathing or sneezing. Painful symptoms of digestive tract disorders tend to appear after eating, and are noticeable within half an hour to an hour after eating, with some relief in 1-2 hours. If the pain persists, it is a sign of a more serious condition, and it is recommended to go to the hospital as soon as possible for treatment.