Treatment of lacunar cerebral infarction within 6 hours of onset is the best time for treatment, and 14 days is generally the critical period for treatment of cerebral infarction in patients who cannot be thrombolized. However, asymptomatic lacunar cerebral infarction is sometimes not easily detected, and if detected in imaging examinations it also requires aggressive and standardized treatment. Lacunar cerebral infarction is a small penetrating artery in the cerebral hemisphere or deep brainstem that has a lesion in the vessel wall based on long-term hypertension, resulting in lumen occlusion and the formation of small infarct foci with cystic lesions of 0.2-15 mm in diameter. Lacunar cerebral infarction usually has no obvious headache and no impairment of consciousness, mainly manifesting as simple motor light hemiparesis, dysarthria-hand clumsiness syndrome, or sensory stroke, ataxic light hemiparesis, etc. The disease is often recurrent and can cause multiple lacunar cerebral infarcts with cognitive impairment, dementia, and Parkinson’s syndrome. Significant improvement is usually seen after individualized treatment for the cause within 6 hours of onset. The prognosis of lacunar cerebral infarction is generally good, but it is prone to recurrent attacks and therefore disease recurrence needs to be prevented.