Tadalafil tablets and dapoxetine hydrochloride tablets, belong to two different drugs, applicable to different people, can not compare the advantages and disadvantages of the therapeutic effect of the two drugs. According to the instruction of the drug, tadalafil tablets are used for the treatment of erectile dysfunction, and cannot be used for children; while dapoxetine hydrochloride tablets are mainly used for the treatment of premature ejaculation, and are used for male patients between 18 and 64 years of age, and the indications of the two drugs are different. The contraindications of the two drugs are also different, tadalafil is prohibited for those who are allergic to any of the ingredients in the product, patients who are taking any form of nitrate drugs, guanylate cyclase stimulators, women, children and other groups of people; the contraindications of Dapoxetine Hydrochloride Tablets are relatively more, in addition to drug allergies, but also include more severe heart failure, moderate to severe liver injury and many other situations. In conclusion, the indications and contraindications of the two drugs are different, and the advantages and disadvantages of the drugs can not be directly compared; however, the two drugs belong to the prescription drugs, and must be used safely under the correct guidance of the physician.