There is no medical research showing that chicken gizzards are effective in treating headaches, so patients with headaches should identify the cause and treat it. Chicken gizzard is a kind of food, containing fat, protein, minerals and other nutrients, is not a drug, no treatment effect. Many kinds of causes can lead to headache, the more common is the headache caused by intracranial lesions, such as meningitis, cerebral vascular lesions, intracranial masses, epileptic headache, intracranial injuries and so on. There are also some headaches caused by extracranial head and neck lesions, such as vascular headaches, head and neck neuroinflammatory headaches, headaches caused by lesions of the five senses and the oral cavity. Also included are headaches caused by some psychiatric disorders. The cause of headache should be identified as soon as possible, and targeted treatment should be chosen according to the specific disease. Headache patients should consult a doctor in time, through the cranial CT, EEG and other tests to confirm the diagnosis, under the guidance of the doctor active treatment, strictly comply with the doctor’s instructions for medication, do not blindly take the food and drugs without medically proven efficacy, in order to avoid the adverse consequences.