There is no obvious difference between paroxetine and fluoxetine in terms of efficacy, and it is related to a variety of factors such as the patient’s personal constitution and the severity of the disease.
Paroxetine is a phenylpiperidine derivative, but also a selective 5-HT reuptake inhibitor, antidepressant effect, can also be used for the original fear disorder, social phobia and obsessive-compulsive disorder treatment. When taken orally, copaxetine is completely absorbed, with a bioavailability of 50%, and is not affected by food or medication.
Fluoxetine is also a selective 5-HT reuptake inhibitor, but it has a low affinity for adrenergic, histaminergic, and cholinergic receptors, is less potent, and correspondingly produces fewer adverse effects.
Several relevant studies have shown that there is no statistically significant difference between the two drugs, either in terms of efficacy or adverse effects.