Topical glucocorticoid-like preparations are one of the commonly used topical drugs in dermatology, but in recent years clinical abuse has caused fear in many patients. First, the topical glucocorticoid hormone preparations are often clinically divided into four categories: super potent, strong, moderate and weak. Ultra-strength hormone and strong hormone is suitable for heavy, hypertrophic skin lesions. For example, beclomethasone propionate ointment, halometasone cream, fludrocortisone acetate ointment. Medium-acting hormones are suitable for mild to moderate lesions. For example: hydrocortisone butyrate ointment, fluticasone propionate cream, tretinoin cream, etc. Weak-acting hormones are suitable for mild and moderate lesions. Commonly used weak hormones are: dianabed ointment, hydrovinylprednisone acetate ointment, dexamethasone acetate ointment and so on. Indications and contraindications 1. Indications: dermatitis and eczema skin diseases, erythematous scaly skin diseases, autoimmune skin diseases, cutaneous vasculitis, non-infectious granuloma, vitiligo, pemphigus vulgaris, proliferative scarring. 2. Contraindications: Allergy to glucocorticoids or their substrates and other components is an absolute contraindication. Various infectious skin diseases. Adverse reactions Long-term massive application may induce or aggravate local infection, skin atrophy, capillary dilatation, hirsutism, pigmentation changes. Precautions 1.Initial strength selection: The primary factor to be considered in the selection of topical hormones is the type of dermatosis and the nature of the lesions. The principle is to first choose the smallest strength of adequate strength hormones. Generally keratinized, mossy or hypertrophic lesions as well as lesions of discoid lupus erythematosus, vitiligo, pemphigus, herpetic pemphigoid and other diseases should be preferred to the strongest strength hormone; mild erythema, tiny pimples or desquamative lesions, especially lesions on the face, periocular area, neck, armpit, inguinal area, inner femur, pubic area, and other tender parts of the body should be preferred to the weakest strength hormone. 2. Super-strength hormone and strong hormone should not be used for a long time on a large area, generally should not be used for more than 2 weeks; generally should not be used on the face, breast, pubic area and folded parts. 3. Pregnant or lactating women: weigh the pros and cons of caution. 4. Infants, children and the elderly: generally choose weak, moderate or soft hormones such as mometasone furoate.