Urine protein less than 150mg/24h is normal, urine protein 3.5g/24h suggests a large amount of proteinuria, urine protein 10g/24h is more serious, need to clarify the cause of the disease, timely treatment.
Nephrotic syndrome is characterized by massive proteinuria, hypoproteinemia, hyperlipidemia, and edema. Urine protein 10g/24h tends to be more serious, mostly due to nephrotic syndrome. The common causes of nephrotic syndrome include membranous nephropathy and diabetic nephropathy.
Membranous nephropathy is antibody-mediated, characterized by the deposition of immune complexes on the epithelial side of the glomerulus, causing sublethal injury to the podocytes and disruption of the glomerular filtration barrier, ultimately leading to proteinuria and other manifestations of nephrotic syndrome. Diabetic nephropathy is one of the most common microvascular complications of diabetes mellitus, which needs to be treated promptly when large amounts of proteinuria occur.
Patients with urinary protein 10g/24h should go to the hospital in time, under the guidance of professional physicians to clarify the cause and timely treatment.