Burning pain in the stomach is common in gastric ulcer, duodenal ulcer, gastroesophageal reflux disease or esophagitis, esophageal erosion, etc., but also can be common in the early stage of gastrointestinal cancer, such as gastric ulcer, duodenal ulcer, in addition to a slight pain in the abdomen will also be belching, acid reflux, with obvious seasonal cyclicity. The pain is often obvious before or after meals. Clinically, oral acid suppression, gastric mucosa protection, anti-Helicobacter pylori drugs are usually used for conservative long-term treatment, such as omeprazole, metronidazole, bismuth potassium citrate and anti-Helicobacter pylori, such as lansoprazole, rabeprazole, and so on. Gastroesophageal reflux disease is usually caused by the lesion of the esophagus itself and the relaxation of the cardia at the gastroesophageal junction, and in severe cases it can also suffer from esophageal hiatal hernia, which can be treated by surgery or conservative treatment with medication, mainly depending on the clinical diagnosis and the severity of the symptoms, and if it is the early stage of gastrointestinal malignant tumors, it can also be detected through the electronic gastrointestinal microscopy, and the pathology of the tissues found to be suspected of malignant lesions can be examined, so that the clinical diagnosis can be confirmed for clinical analysis. The diagnosis is confirmed for clinical analysis, early detection and early treatment, usually with a good prognosis.