The survival time of AIDS patients with CD4 lymphocytes lower than 20 varies from person to person, usually related to the treatment time and treatment method, such as timely treatment of the condition stabilization survival time limit can be 10-20 years, if the treatment is not timely survival time limit may be within 1 year. CD4 cells are a kind of white blood cells, belonging to the human body is very important immune cells, is the main target of HIV attack, generally CD4 cells less than 200 indicates that has entered the AIDS stage, and CD4 value is less than 20 indicates that the AIDS longer, and the virus has destroyed the body’s immune system, resulting in low immune function, there may be a variety of opportunistic infections or tumors. After the diagnosis of HIV infection, regardless of the CD4 lymphocyte level is high or low, need to receive anti-retroviral treatment early, most patients after regular treatment, life expectancy can be greatly prolonged, the specific survival time needs to be combined with the patient’s own nutritional health status and the sensitivity of the drug tolerance, if the condition is controlled and stabilized, the general survival of 10-20 years is also possible; if the timely treatment and intervention is not carried out, the survival time limit is generally within one year. Without timely treatment and intervention, the survival timeframe is generally within one year. Therefore, AIDS patients with CD4 cells less than 20 are recommended to seek timely medical treatment and follow the doctor’s instructions for standardized treatment to avoid aggravation of the disease.