If the blood pressure is still high even after taking antihypertensive drugs, it may be caused by unsatisfactory control of primary hypertension or secondary hypertension. If it is primary hypertension, further control of blood pressure can be achieved by lifestyle improvement, drug dosage increase, or combination of drugs. If it is secondary hypertension, it needs to be treated according to the cause of the disease. 1. Primary hypertension: (1) Improvement of life style: it is the foundation of good control of blood pressure for hypertensive patients, common methods include weight control, pay attention to rest, avoid late night and laboriousness, have a good mood, avoid mental stress, diet should be low-salt and low-fat diet, and do not drink alcohol and smoke. (2) Medication adjustment: Drug dosage can be increased or a combination of drugs can be taken to further control blood pressure, the common combination of drugs are angiotensin-converting enzyme inhibitors (ACEI), such as enalapril/angiotensin II receptor inhibitors (ARB), such as valsartan, + dihydropyridine calcium antagonists (CCB), such as nifedipine; ARB/ACEI + thiazide diuretics, such as hydrochlorothiazide; CCB; ARB/ACEI + thiazide diuretics, such as hydrochlorothiazide; CCB; ARB/ACEI + thiazide diuretics. e.g. hydrochlorothiazide; CCB + thiazide diuretics; CCB + beta-receptor antagonists such as metoprolol. 2. Secondary hypertension: some patients with hypertension may be due to a combination of secondary factors, requiring targeted etiologic treatment. Such as pheochromocytoma surgical resection treatment; hyperthyroidism follow the doctor’s instructions to take drugs such as propylthiouracil tablets, methimazole, etc.; renal artery stenosis interventional surgery treatment. When the blood pressure control is not satisfactory, it is recommended to go to the hospital outpatient clinic, under the guidance of the doctor for a comprehensive analysis to develop a treatment plan, do not blindly adjust the medication, in order to avoid accidents.