In clinical practice, patients can have many kinds of lesions in the knee joint area, so they can be treated with a variety of creams, but the appropriate creams should be taken according to the specific disease. Patients with localized rheumatism pain in the knee joint due to cold need to choose rheumatism pain relief creams with the ability to dispel wind and dampness to be applied externally. If the patient’s knee is swollen and painful due to chronic strain or trauma, the patient needs to choose ointments that have the effect of activating blood stasis and relieving swelling and pain, such as Wan Tong Tendon and Bone Patch, Activating Blood Pain Relief Ointment, Jin Huang Ointment, and Eliminating Knot Ointment, as well as Yunnan Baiyao Aerosol and Futalin Ointment, or use orthopedic lotions to fumigate the knee.