Heart discomfort like a blockage may be caused by angina pectoris, cardiac neurosis and other diseases, which can be treated by sedation, vasodilator medication and surgical intervention. Because of individual differences, you need to choose the appropriate drugs under the guidance of the doctor. 1. Angina pectoris: Angina pectoris is a clinical syndrome of ischemia and hypoxia of the heart caused by insufficient blood supply to the coronary arteries. Clinical manifestations of chest pain after physical activity or emotional excitement, the attack will also be accompanied by chest tightness, panic and other symptoms. Nitrate drugs such as nitroglycerin can dilate blood vessels and relieve the symptoms of chest tightness. If the condition is serious, percutaneous coronary intervention can be used to unblock blood vessels. 2. Cardiac neurosis: cardiovascular disease caused by mental or nervous dysfunction. The main clinical symptoms are palpitations, dyspnea, chest tightness and congestion around the heart, and anxiety can be relieved by sedative drugs such as alprazolam. Patients should go to the hospital immediately when they feel unwell.