The main reason why IgA nephropathy cannot be replaced is that IgA nephropathy will recur after kidney transplantation. Other possible reasons include the patient’s body cannot tolerate it, such as diseases combined with cardiopulmonary insufficiency, gastrointestinal ulcers, mental disorders, etc. Patients with heart disease may become worse after kidney transplantation because of heart disease; patients with peptic ulcers may aggravate the ulcers.
Heart disease patients may become worse after kidney transplantation, so they should treat their heart disease first; peptic ulcer patients using immunosuppressants and hormones after kidney transplantation may aggravate their ulcers, which may lead to peptic hemorrhage in severe cases; patients with mental disorders are also not eligible for kidney transplantation.
IgA nephropathy usually manifests as asymptomatic hematuria, some patients have proteinuria, edema and hypertension, etc. Kidney transplantation is usually unnecessary. However, when renal function progresses to uremia stage, renal replacement therapy is needed, and renal transplantation is the best renal replacement therapy at present if conditions permit.
Patients with IgA nephropathy are advised to go to regular hospitals in time and get targeted treatment or therapy under the guidance of doctors.