Temporary sealing medications used during root canal treatment include pulp inactivators, calcium hydroxide, and phenolic compounds. Root canal treatment for the first time sealing drugs due to the sealing of different drugs, can not exceed the time of about 3 to 14 days ranging. 1. Endodontic inactivator: endodontic inactivator has fast inactivator arsenic trioxide, slow inactivator paraformaldehyde and so on. Generally, the fast inactivator sealing time is about 2 days, not more than 3 days at most; slow inactivator generally takes about 7 days, not more than 14 days at most. 2. Calcium hydroxide: Calcium hydroxide is a commonly used clinical root canal disinfectant, which is biocompatible, safe and can stimulate bone tissue formation. The effective time of the drug is generally about 7 to 14 days, so the general sealing should be about 7 days, not more than 14 days at most. 3. Phenol disinfectant: It is a disinfectant with a long history of use, but because of its toxicity and sensitization, it is now used less and less in clinical practice. The sealing time is generally 5-7 days. Those who need root canal treatment for tooth discomfort should consult the doctor in time, complete the examination, and have it done by a professional dentist in order to achieve good results.