Metronidazole, also known as methotrexate, has the effect of fighting anaerobic infections and antitrichomonas. Every drug has adverse reactions. The most common adverse reactions to metronidazole, both oral and intravenous, are gastrointestinal reactions, such as nausea, vomiting, anorexia, and decreased appetite. It can also cause a decrease in white blood cells, skin rash, and drug allergy. Liver function damage is extremely rare and does not usually occur. So try to use the drug after meals, not under an empty stomach, you can give B6 and other symptomatic treatment. The symptoms of adverse drug reactions usually disappear naturally after stopping the drug.