IVF can be done with high sperm count malformation and low motility. It is only necessary to choose either first generation IVF or second generation based on sperm quality. For men with normal semen or mild oligo, weak, or dysmorphic spermatozoa, the first generation of IVF can be considered, in which the sperm and egg are fertilized outside of the body. For men with severe oligo, weak, or abnormal spermatozoa, or obstructive azoospermia, they need to undergo second-generation IVF, in which a doctor injects the man’s sperm into the woman’s egg under microscopic operation. Men need to pay attention to abstaining from sex for 3~7 days before the sperm retrieval, as well as avoiding contact with tobacco, alcohol and other items. Meanwhile, men need to relax during the process of sperm retrieval, avoiding too much psychological tension and stress, which may lead to the inability to discharge the semen.