Failure to pass stool may be caused by physiological factors, gastrointestinal diseases and anal diseases. It is recommended to pay attention to life and dietary adjustments, if necessary, to give appropriate medication, can promote the discharge of stool. 1. Physiological factors: often eat refined food, fresh vegetables and fruits, insufficient water intake, usually less exercise, resulting in slow gastrointestinal peristalsis, stools are difficult to discharge. It is recommended to increase the intake of vegetables and fruits and water, increase the amount of exercise, and perform clockwise abdominal rubbing, which is conducive to the discharge of stools. 2. Gastrointestinal diseases: Gastrointestinal diseases, such as slow gastrointestinal peristalsis, gastrointestinal dysfunction, intestinal flora imbalance, may lead to difficulty in passing stools. It is recommended to give domperidone and cisapride under doctor’s guidance to increase the power of gastrointestinal tract. Probiotics, such as bifidobacteria, can also be given to regulate intestinal flora. 3. Anal diseases: anal diseases such as hemorrhoids, anal fissure, defecation will cause local irritation, resulting in pain, not dare to defecate. It is recommended to consult the anorectal department of the hospital, under the guidance of the doctor to give hemorrhoid cream, hemorrhoid suppository, or through the surgical way of treatment. Often can not poop, it is recommended to go to the hospital gastroenterology, to understand whether it is related to pathological factors, but also targeted to give the appropriate drugs for treatment. Drugs need to be used under the guidance of a professional physician, not self-medication.