Heartburn is unlikely to be solved in one move, heartburn may be caused by gastroesophageal reflux disease, gastric ulcers, medication factors, etc., need to be targeted to take the general treatment, medication, etc., commonly used medications such as omeprazole, moxapride, bismuth potassium citrate. 1. Gastroesophageal reflux disease (GERD): mainly due to the reflux of gastric contents into the esophagus, causing local irritation caused by the symptoms, generally need to take acid-suppressing drugs and gastric power drugs, such as omeprazole, lansoprazole, moxapril, itopride, and so on. 2. Gastric ulcer: may be due to irregular diet or smoking and other reasons, due to the gastric mucosa is seriously damaged, ulcers easily lead to heartburn, in addition to taking acid-suppressing drugs and gastric motivation drugs, but also with the promotion of mucosal repair drugs, such as bismuth potassium citrate, aluminum sulfate and so on. 3. Drug factors: such as taking non-steroidal anti-inflammatory drugs, anticholinergic drugs, etc., may lead to heartburn, usually after stopping the drug, the symptoms gradually alleviate, if necessary, can also be oral acid-suppressing drugs. If the symptoms of heartburn continue to be unrelieved, it is recommended that the patient consult a doctor in a timely manner to identify the cause and cooperate with the doctor’s treatment.