The diagnosis is made on the basis of the clinical manifestations and the characteristic whitening of all or part of the hair. White hair has been documented in Chinese medicine for a long time, such as the “Treatise on the Origin of Diseases”, which states: “The meridian of Shao-Yin, the kidney is the master of bone marrow, and its flower is in the hair. If the blood is strong, then the kidney is strong, then the bone marrow is full, so moist and black; if the blood is weak, then the kidney is weak, the kidney is weak, then the bone marrow is exhausted, so the hair becomes white. Clinically, it can be divided into the following categories: 1, congenital generalized albinism: with albinism, the whole body hair is grayish white, the skin and iris are lack of pigment. 2, congenital limited albinism: most have a family history of one or more areas of limited white hair in a certain part of the body, sometimes the eyebrows and eyelashes become partially white. If the hair is ring-shaped pigment loss, known as ring-shaped leukomalacia. 3, senile gray hair: is a manifestation of aging, generally after the age of 40, mostly in the temples, gradually each ministry hair can become white. 4, adolescent gray onset: common in adolescents, also known as premature gray onset. Initially the hair has sparse scattered in a few gray hair, and later can gradually or suddenly increase. If it occurs suddenly, it may be related to nutritional disorders. In all types of leukomalacia, there is usually no discomfort other than gray hair. The diagnosis is made based on the above clinical manifestations and the characteristic graying of all or part of the hair.