Ovulation injections are one of the common modern treatments for assisted conception. Ovulation injections contain two gonadotropins, FSH and LH, which promote follicle development and estrogen secretion. If the pituitary gland and ovaries are functioning, the positive feedback of estrogen produced can indirectly induce ovulation by the pituitary gland producing sufficient LH. If the pituitary gland is not functioning, additional chorionic gonadotropin is required to induce ovulation and maintain luteal function. In conclusion, ovulation stimulation stimulates ovulation in the body, which can be beneficial to a certain extent for women of advanced age to get pregnant or to help women to conceive twins. Although ovulation promotion is an effective means of assisting fertility, it is not a panacea for seeking a child. It also has various contraindications and risks, such as a low success rate for women over 35 years old, and may cause a series of side effects: 1. Excessive estrogen levels Because ovulation promotion drugs block the feedback of estrogen to the hypothalamus, the body stays at a high estrogen level, which may cause ovarian hyperstimulation syndrome-endocrine disruption, water-electrolyte imbalance, pelvic and abdominal fluid accumulation and even blood clots. High estrogen levels also accelerate the growth of breast tumors and ovarian cysts. 2, causing other complications Abuse of ovulation pills leads to diseases on the body If a normal person takes ovulation pills, ovulation suddenly increases, and it is difficult for the normal body to withstand such changes, which can also lead to other complications, such as ovarian cysts, ovarian rupture, embolism, electrolyte disorders, ovarian hyperstimulation syndrome, etc., which can bring liver and kidney failure, thoracic ascites and other consequences to pregnant women, and in serious cases, even lead to amputation and Shock. 3. Pregnancy complications caused by multiple births Multiple births can cause pregnancy complications, the probability of gestational hypertension syndrome, preterm labor and miscarriage will greatly increase, and the heart, liver and kidneys of pregnant women will be overloaded. During delivery, most of them will suffer from hemorrhage, DIC (diffuse intravascular coagulation), heart failure and even shock. 4. Early menopause The limited number of follicles and the long-term promotion of accelerated follicular development and maturation will inevitably lead to rapid depletion of more than 40,000 follicles in reserve at puberty. When all the follicles are depleted, menopause will come as estrogen is no longer secreted. What other common questions do you have about ovulation injections? 1. Why are my follicles growing less and less after the ovulation injection? Is this normal? A: The number of growing follicles depends on the function of the ovaries and their response to the ovulation medication, and the dose of ovulation medication is also a factor. If there are many basal follicles but few growing follicles, it may be a case of poor ovarian response to ovulation promotion. 2.What should I do if I don’t ovulate even after the ovulation promotion injection? Can I get pregnant with 32*23mm follicles and 11mm thick lining? Follicle 32*23mm is too large and it is very likely that the follicle will not be ovulated, which is a great side effect of the ovulation injection. Ovulation disorders are mostly caused by endocrine diseases. It is recommended to check the endocrine level in detail to clarify the cause of non-ovulation; it is not recommended to use ovulation drugs blindly to avoid ovarian hyperstimulation or miscarriage, which may affect conception. It is recommended to combine the endocrine examination results for drug regulation. 3.What should I do if my follicles do not grow? I used to ovulate with clomiphene, but now I don’t ovulate with the drug, is it because I am not sensitive to the drug? The factors that cause ovulation disorders are: central nervous system anovulation; hypothalamic anovulation; pituitary anovulation; ovarian anovulation; polycystic ovary syndrome; follicular luteinization non-rupture syndrome. Other: endocrine system other than gonads such as thyroid and adrenal cortex dysfunction, some systemic diseases such as severe malnutrition can affect the regulation of ovarian function and lead to ovulation disorders. It is recommended to go to the hospital for detailed examination to clarify the cause and treat the symptoms!