Most gastric perforations are caused by gastric ulcers, and when the ulcer lesions develop deeper, they can penetrate the plasma membrane layer of the stomach and cause gastric perforation, which can be characterized by severe pain throughout the abdomen and may require surgical repair of the perforation. Gastric erosion means that the erosive lesion is limited to the mucosal layer of the stomach and does not reach the muscular layer, so the erosion is relatively light. Generally, oral acid suppressants combined with gastric mucosal protective agents, such as omeprazole plus rehabilitative new liquid or bismuth, etc., the specific use of drugs need to consult the gastroenterology doctor. In case of gastric perforation, patients need to be treated urgently to avoid life-threatening consequences.