Neurodermatitis, also known as chronic lichen simplex, is mainly treated with general treatment, medication and physical therapy. 1. General treatment: first of all, we should pay attention to avoid the use of irritating skin care products, improve the rough way of bathing, and avoid scratching and rubbing the skin in daily life. 2. Medication: (1) local drug therapy: can be used externally glucocorticoid hormone preparations external coating, such as fluoro easy, tretinoin, betamethasone, etc., can play a role in anti-inflammatory and eliminating itching and other uncomfortable symptoms, after the application of medicine can be used after a short period of time to seal sealing the package, the effect is better; secondly, can also be used in the tar type of preparation, such as black bean distillate ointment, pine distillate ointment, etc., but also can play a role in dissolving the role of keratin. (2) systemic drug therapy: oral antihistamines, such as loratadine and cetirizine, can effectively relieve itching and other uncomfortable symptoms, but is likely to cause drowsiness and other adverse reactions; for the lesions are widely distributed and accompanied by intense itching of the patient, can also be used in procaine mixed with 5% dextrose solution for intravenous drip treatment. 3. Physical therapy: In addition, phototherapy or liquid nitrogen freezing, helium-neon laser irradiation and other methods of treatment, can play a role in relieving the lesions. Specific treatment methods should be reasonably adopted under the guidance of professional doctors.