Eusebio is a short-acting contraceptive pill, mainly a compounded preparation of estrogen and progestin, which needs to be absorbed through the gastrointestinal tract after women take it. Therefore, it may cause adverse effects on the body, most notably nausea, vomiting and other gastrointestinal reactions after taking the pill. A small number of women may also suffer from water and sodium retention, which may lead to weight gain, or pigmentation on the face, leading to chloasma. Women may also suffer from irregular vaginal bleeding if they miss a dose. Long-term use of Eusemide may also lead to thrombotic disorders, such as cerebral thrombosis or lower extremity vein embolism.