Consider strain injury, calcium deficiency, rheumatoid arthritis, gout, etc. for pain in the big fishbone of the hand and the heel. 1. Strain: prolonged continuation of a certain action, or over-exertion will trigger muscle strain, resulting in aseptic inflammation, pain, this symptom can be reduced through rest, hot compresses, massage. 2. Calcium deficiency: It can also cause pain, and some may have cramps. Symptoms can be reduced by calcium supplementation. 3. Rheumatoid arthritis: it can cause pain in the joints, joint swelling, and limited joint movement. Oral anti-rheumatic drugs, such as diclofenac sodium enteric-coated tablets or nimesulide capsules, can be improved under the guidance of a doctor. 4. Gout: If the local redness, swelling and pain, consider the possibility of gout, through the test of uric acid can be clearly diagnosed, under the guidance of the doctor to apply febuxostat or allopurinol. Hand pain and heel pain if the rest did not reduce, it is recommended to go to the hospital in time to check, under the guidance of the doctor for treatment.