Thyroid nodule 4a is graded under thyroid ultrasound, thyroid nodule 4a malignancy rate of 2% to 10%, thyroid nodule 4a discomfort, the patient can first undergo fine needle aspiration cytology biopsy. If it is a thyroid adenoma, surgical resection and medication can be chosen. If it is thyroid cancer, surgical treatment, radiotherapy, chemotherapy, and medication are needed for improvement. 1. Thyroid adenoma: Thyroid adenoma is a benign thyroid tumor and the most common one. Medications, such as levothyroxine, can be chosen to inhibit the growth of thyroid cells and reduce the size of thyroid nodules. If the symptoms are severe, surgery can be considered to remove them. 2. Thyroid cancer: For patients with thyroid cancer, surgery should be preferred, which requires treatment of primary foci as well as treatment of lymph nodes in the neck. For patients with undifferentiated thyroid cancer, total thyroidectomy can be considered. After surgery, radiotherapy, chemotherapy and drug therapy are needed to enhance the efficacy. For patients with thyroid nodule 4a who are not feeling well, they should consult a doctor in time and cooperate with the doctor for standardized treatment.