Anal fissure is not malignant; anal papillary hypertrophy usually has the possibility of malignant change, but the general chance of malignant change is very small, it is recommended to consult the doctor in time. Anal fissure is a benign disease that occurs mainly due to violent injury to the anal skin, and common triggers include dry stool, habitual constipation, diarrhea, and so on. The main manifestations of anal fissure are blood in the stool and severe pain in the anus. The anal papilla is located near the dentate line of the anus, if this area is stimulated by anal fissure, hemorrhoids and other chronic inflammation may lead to anal papillary hypertrophy, if not treated in time, the affected area may grow a sarcoma-like object, which may lead to lesions, and at the same time, the patient may have anal itching, pain, defecation and other symptoms. If the patient has anal fissure, anal papillae hypertrophy can be under the guidance of the doctor to expand the anus surgery, longitudinal cut transverse suture method, electrocautery and other surgical methods for treatment. Patients should pay attention to perianal hygiene to keep dry and clean. Prohibit spicy and stimulating food, eat less greasy and fried food, eat more vitamin-rich fruits and vegetables, prevent constipation, diarrhea, etc., while quitting smoking and alcohol. It is recommended that patients go to the hospital in time for consultation and treatment, do not use drugs privately, so as not to cause danger.