There are many reasons for children to vomit in the middle of the night, for the improper feeding caused by the main to improve the feeding mode, for the disease caused by the main to the etiological treatment and symptomatic supportive treatment. 1. Improper feeding: too much breastfeeding, lying down after breastfeeding or too much breastfeeding, early turning and other improper feeding may cause children to vomit in the middle of the night, mainly through the improvement of the feeding method, scientific feeding to alleviate, such as controlling the amount of pre-bedtime feeding and so on. 2. Pathological vomiting: gastrointestinal diseases may cause children to vomit in the middle of the night, the treatment mainly includes symptomatic and etiological treatment. Such as acute gastroenteritis caused by pediatric vomiting in the middle of the night should pay attention to hydration, where bacterial infection caused by the use of antibiotics as prescribed by the doctor, such as cefaclor, cefixime, etc., to help improve the condition and relieve the symptoms of vomiting. In addition does not rule out other diseases, when the symptoms of pediatric vomiting in the middle of the night and a long time has not been relieved, should be timely to the regular hospital, and under the guidance of the doctor for treatment.