Oligodendrocytoma grade II is not benign. Oligodendrocytoma belongs to a type of glioma, and clinically it is customary to refer to World Health Organization (WHO) grade II gliomas as low-grade gliomas. Oligodendrogliomas tend to develop in the frontal and temporal lobes of the brain, grow slowly, and often present with epilepsy as the first symptom. The imaging features of oligodendrogliomas are often accompanied by calcification, which will show high-density calcified shadows on CT. Surgical resection is usually required, followed by radiotherapy or chemotherapy. Treatment of oligodendrogliomas is effective, and aggressive treatment can extend the life expectancy of patients with oligodendrogliomas.