The sensation of bugs crawling above the ankles may be caused by pruritis, peripheral or peripheral neuritis, and other factors. 1. Pruritus: Pruritus is a skin symptom with only itchy skin and no primary skin damage. It is mainly divided into limited pruritus, generalized pruritus. If limited pruritus occurs in the ankle area, it may lead to a localized anthropomorphic sensation. 2. Peripheral or peripheral neuritis: Peripheral neuritis is an inflammatory reaction that occurs when the peripheral nerves are damaged by a variety of factors. Peripheral neuritis is associated with infectious diseases, metabolic diseases, hereditary diseases, immune diseases and other factors. The main manifestations are numbness, abnormal sensation, and sensory hypersensitivity in the hands, feet, and limbs, such as a sensation like ants crawling or pins and needles. The feeling of crawling insects in the ankles, but also to understand whether it is related to the symptoms of nerve entrapment caused by obesity. It is recommended to go to the dermatology department of the hospital, after clarifying the cause of the disease, standardized treatment under the guidance of the doctor.